Embedded Files
Highlights
RLD Labitigan*, A Sanborn*, C Hao, C Chan, N Belliveau, E Brown, M Mehrotra, J Theriot. (2022). Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening. bioRxiv, 2022-12.
A Sanborn †, B Yeh, J Feigerle, C Hao, R Townshend, E Aiden, R Dror, R Kornberg †. (2021) Simple biochemical features underlie transcriptional activation domain diversity and dynamic, fuzzy binding to Mediator. eLife, 10, e68068. († corresponding author)
A Sanborn*, S Rao*, N Durand, M Huntley, A Jewett, I Bochkov, D Chinnappan, A Cutkosky, S Huang, J Li, D McKenna, E Stamenova, E Lander, E Aiden. (2015) Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes. PNAS 112(47).
Featured in over 20 media outlets, including TIME, Science, The Atlantic, Science News, and Houston Chronicle (front page). Our highlights video also won the 2016 Lab Grammies!
Selected publications
See also: Google scholar profile
M Viana, J Chen, T Knijnenburg, R Vasan, C Yan, ... (73 authors) ... A Sanborn, G Johnson, R Gunawardane, N Gaudreault, J Theriot, S Rafelski. (2023). Integrated intracellular organization and its variations in human iPS cells. Nature 613 (7943).
L Vian*, A Pekowska*, S Rao*, K Kieffer-Kwon*, S Jung*, L Baranello, S Huang, L El Khattabi, M Dose, N Pruett, A Sanborn, ... (16 authors) ... J Onuchic, Y Ruan, A Nussenzweig, D Levens, E Aiden, R Casellas. (2018). The energetics and physiological impact of cohesin extrusion. Cell, 173, 1-14.
S Rao, S Huang, B St Hilaire, J Engreitz, E Perez, K Kieffer-Kwon, A Sanborn, S Johnstone, G Bascom, I Bochkov, X Huang, M Shamim, J Shin, D Turner, Z Ye, A Omer, J Robinson, T Schlick, B Bernstein, R Casellas, E Lander, and E Aiden. (2017). Cohesin loss eliminates all loop domains. Cell, 171(2).
E Darrow*, M Huntley*, O Dudchenko, E Stamenova, N Durand, Z Sun, S Huang, A Sanborn, I Machol, M Shamim, A Seberg, E Lander, B Chadwick, E Aiden. (2016). Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture. PNAS, 113(31).
W Huang*, A Manglik*, AJ Venkatakrishnan, T Laeremans, E Feinberg, A Sanborn, H Kato, K Livingston, T Thorsen, R Kling, S Granier, P Gmeiner, J Traynor, W Weis, J Steyaert, R Dror, B Kobilka. (2015) Structural insights into mu-opioid receptor activation. Nature, 524(7565), 315-321.
S Rao*, M Huntley*, N Durand, E Stamenova, I Bochkov, J Robinson, A Sanborn, I Machol, A Omer, E Lander, E Aiden. (2014) A 3D map of the human genome at kilobase resolutionreveals principles of chromatin looping. Cell 159(7), 1665-1680.
Featured in over 60 international media outlets, including NPR, Science, NIH blog, KQED, Science News, Houston Chronicle, Broad Institute, Harvard, and Baylor. Our paperflick won the 2015 Lab Grammies!
A Sanborn. Scaling Dimensions with Fractal Curves and Applications to DNA Folding. Undergraduate thesis, Harvard University, 2011.
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